Paroxetine or Paxera: Why Do We Use It?

Paroxetine, also known by the brand name Paxera, is a common antidepressant medication used to treat depression, anxiety disorders, and other conditions. It is a serotonin-norepinephrine reuptake inhibitor (SNRI) that works by blocking the absorption of serotonin and norepinephrine into the nerve cells, increasing their availability in the brain. While it can be an effective treatment for many people, it can also cause side effects such as nausea, headaches, and sexual dysfunction. In some cases, switching to a different medication may be necessary.

Is Paxera addictive?

Paxera is not addictive. However, it is possible to develop a psychological dependence on Paxera. If you feel like you need to take Paxera in order to feel normal or cope with daily life, then it is recommended that you talk to your doctor about your use of the medication.

Paxera is not addictive in the sense that it causes physical withdrawal symptoms when discontinued. However, some people may find that they are unable to function normally without taking Paxera and thus may feel psychologically dependent on the drug. If this is the case for you, please consult with your doctor about your use of Paxera.

paroxetine paxera
paroxetine or paxera: why do we use it? 2

What Is Paroxetine?

It is a medication that is used to treat various mental health conditions, including depression, anxiety, and obsessive-compulsive disorder. It belongs to a class of medications called selective serotonin reuptake inhibitors (SSRIs) and works by increasing the amount of serotonin in the brain. Selective serotonin reuptake inhibitors (SSRI) are a type of antidepressant medication. They work by increasing levels of serotonin in the brain. Serotonin is a neurotransmitter that plays an important role in mood, emotions, and thinking.

SSRI medications are effective for the treatment of major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, posttraumatic stress disorder, and premenstrual dysphoric disorder.


A number of meta-analyses have been done to measure the effectiveness of paroxetine in depression. They’ve come up with various conclusions, including that it is more effective than placebo and that it compares favorably to other antidepressants. Despite this, there was no compelling evidence that it performed better or worse than other antidepressants in terms of increased response to treatment at any time.

Paroxetine was the first antidepressant to be given a regulatory go-ahead in the United States for the treatment of panic anxiety. Several studies have found that it is more effective than a placebo in treating panic disorder.

It has shown to be effective in the treatment of social anxiety disorder in both adults and children. It can also help those who have co-occurring social anxiety disorder and alcohol use problem. It appears to work similarly to other SSRIs.

Paroxetine is an antidepressant that is commonly used to treat obsessive-compulsive disorder. Paroxetine’s effectiveness versus clomipramine and venlafaxine is comparable. It may also help children with obsessive-compulsive disorder live a more normal life.

Paroxetine is a prescription antidepressant that has been approved for the treatment of post traumatic stress disorder in the United States, Japan, and Europe. It’s only available by prescription in the United States. Paroxetine is FDA-approved for generalized anxiety disorder as well.

In 2013, it was authorized in the United States for the treatment of moderate-to-severe vasomotor symptoms such as hot flashes and night sweats caused by menopause. Side effects are comparable to those of a placebo, and dose tapering is not required for discontinuation with the low dose employed for menopausal hot flashes.

Side Effects:

Side effects include drowsiness, dry mouth, loss of appetite, sweating, sleeplessness, and sexual dysfunction. In those under the age of 25, suicide, serotonin syndrome, and mania are all potential serious side effects. While the rate of adverse effects appears to be comparable to other SSRIs and SNRIs, antidepressant discontinuation syndromes are more common. While use during pregnancy is not suggested, breastfeeding is quite safe.

One of the most frequently reported adverse effects of paroxetine and other SSRIs is sexual function problems, including loss of desire, anorgasmia, vaginal dryness, and erectile dysfunction. Despite the fact that early study results suggested a low incidence of sexual dysfunction, more recent research in which the researcher actively queries about sexual difficulties indicate that the proportion is higher than 70%. Symptoms of sexual dysfunction have been noted to linger after stopping SSRIs, although this is uncommon.

Like other antidepressants, it may cause an increased risk of suicidal thoughts and behavior in persons under the age of 25. In 2004, the FDA conducted a statistical analysis of paroxetine clinical trials in children and adolescents and found an increase in suicidality and ideation as compared to placebo, which was observed in trials for both depression and anxiety disorders. In 2015, a study published in The BMJ that reexamined the original case notes claimed that paroxetine and imipramine were over-rated compared to placebo in adolescent patients with depression.

Last Updated on December 9, 2022 by Lucas Berg


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